Anti-Aging Treatments Available Through Telehealth in 2026

The anti-aging treatments commonly offered through telehealth are NAD+ injections, glutathione injections, peptides such as sermorelin, and hormone therapy. Only hormone therapy includes FDA-approved products, and those are approved for specific medical conditions, not for aging itself; the rest are compounded drugs that FDA has not approved and whose human evidence is thin.
That distinction matters more than any brand name. FDA states plainly that compounded drugs are not FDA-approved and that it does not verify their safety, effectiveness or quality before they are marketed. Drugs from a 503B outsourcing facility must follow current good manufacturing practice (CGMP) rules and are inspected mainly by FDA; drugs from a 503A pharmacy are not held to CGMP and are overseen day to day by state boards of pharmacy. Asking a clinic which kind of pharmacy fills its prescriptions is a reasonable first question.
NAD+ Therapy
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme the body uses in energy metabolism. Clinics sell it as an injection or IV drip made by compounding pharmacies, while NMN and NR are oral precursors sold as supplements. The human research is small. A 2024 systematic review in the American Journal of Physiology: Endocrinology and Metabolism found 10 studies with 489 participants in total, all using oral NADH or NAD precursors rather than injections. Reported side effects included muscle pain, fatigue, sleep disturbance and headaches, none judged serious, and the authors called for more research on specific conditions and doses.
Results for the aging-related outcomes people usually care about have been modest. A 2025 meta-analysis of randomized trials in adults averaging over 60 found that NMN had no significant effect on muscle mass, grip strength or walking speed, and NR gave mixed results; the authors concluded that current evidence does not support NMN or NR for preserving muscle mass and function. Because neither review covered injected NAD+, human data on the form most telehealth clinics sell is thinner still.
Glutathione Injections
Glutathione is an antioxidant the body makes on its own. Injectable glutathione sold by clinics is compounded, so it falls under the same FDA caveat as any compounded drug. The most important recent fact is a safety notice: in August 2026 FDA said it was aware of at least 30 patients who had adverse events after IV glutathione, given alone or mixed with other ingredients, including fever, chills, pain, dizziness, signs of shock and sepsis-like symptoms. Some patients were hospitalized. FDA said the symptoms were consistent with excessive endotoxin exposure and that the glutathione involved was labeled dietary supplement grade, which it called an inappropriate ingredient for injectable drugs. FDA also noted it had raised similar concerns in 2019.
Pro tip: If a clinic offers glutathione shots or drips, ask which pharmacy compounds them and whether the ingredient is pharmaceutical grade. FDA has told compounders not to use dietary supplement grade glutathione in injectables.
Peptide Therapy
Sermorelin is the peptide with the clearest regulatory history. It was once sold as the FDA-approved injection Geref, which was later withdrawn from sale; in 2013 FDA determined that the withdrawal was not for reasons of safety or effectiveness. The sermorelin telehealth clinics prescribe today is compounded, so it is not FDA-approved.
Many other peptides marketed for longevity appear on FDA's page of bulk drug substances that may present significant safety risks (content current as of April 22, 2026). BPC-157, GHK-Cu for injection, thymosin alpha-1, CJC-1295, epitalon and MOTs-C are listed as nominated but withdrawn. FDA's notes include limited human safety data for injectable GHK-Cu, inadequate safety information for thymosin alpha-1, and serious adverse events including increased heart rate for CJC-1295. Ipamorelin is in category 2 for 503B facilities, with FDA citing serious adverse events including death when it was given intravenously. An earlier version of this guide said February 2026 rule changes had restored access to 14 peptides; the FDA pages we checked do not show that, so we removed the claim.
Hormone Therapy
For menopause, FDA says hormone therapy can help hot flashes, night sweats and vaginal dryness and may lower the risk of osteoporosis, but it is not for everyone. For some women it may raise the chance of blood clots, heart attack, stroke, breast cancer and gallbladder disease. FDA advises using the lowest dose that helps for the shortest time needed, and says it has no evidence that compounded "bioidentical" hormones are safer or more effective than FDA-approved products, which already contain hormones identical to those the body makes.
For men, testosterone is a Schedule III controlled substance. The testosterone cypionate label says safety and efficacy have not been established for "age-related hypogonadism", meaning low testosterone due to aging alone. In February 2025 FDA required class-wide label changes: results of the TRAVERSE trial, which found no increase in adverse cardiovascular outcomes in men using testosterone for hypogonadism, were added; cardiovascular-risk language was removed from the boxed warning; blood pressure warnings were added; and the limitation of use for age-related hypogonadism was kept. Because it is a controlled substance, federal and state rules govern how testosterone can be prescribed, including over telehealth.
- •Hormone therapy: FDA-approved products exist for menopause symptoms and for low testosterone caused by a medical condition. Not approved for aging itself; compounded versions are not FDA-approved.
- •NAD+: Injections are compounded and not FDA-approved. Published human studies are small and mostly use oral NADH, NMN or NR.
- •Glutathione: Injections are compounded and not FDA-approved. FDA issued a safety notice about contaminated IV glutathione in August 2026.
- •Peptides: Compounded sermorelin is widely offered. Several other popular peptides are on FDA's safety-risk list; check that page for current status.
What It Costs
Prices vary widely by clinic, product and dose, and many clinics bundle a membership fee, lab work and medication differently, so we do not quote a single range here. Before paying, ask for the ongoing monthly price after any introductory offer, what lab tests are required and what they cost, and how to cancel. Our individual anti-aging provider reviews list the plans each provider publishes.
- 1.Is this product FDA-approved for my condition, or is it compounded?
- 2.Which pharmacy prepares it, and is it a 503A pharmacy or a 503B outsourcing facility?
- 3.What does the clinic know about the human evidence for this treatment, and what outcome should I expect to measure?
- 4.Is the peptide or ingredient on FDA's list of bulk substances that may present significant safety risks?
- 5.What blood tests are done before and during treatment, and who reviews them?
- 6.What is the full ongoing monthly cost, and how do I cancel?
Pro tip: This guide describes public FDA records and published studies. It is not medical advice. Talk to a licensed clinician about whether any of these treatments is appropriate for you.
Anti-aging treatments at a glance
A quick comparison built only from the FDA records and reviews cited on this page.
| Treatment | FDA-approved? | Human evidence | Key caution |
|---|---|---|---|
| NAD+ injections | No, compounded | Small studies, mostly oral NADH or precursors | Little data on injected NAD+ |
| Glutathione injections | No, compounded | Not reviewed here | FDA endotoxin notice, August 2026 |
| Sermorelin | No, compounded (brand Geref withdrawn from sale) | Not reviewed here | Geref withdrawal was not for safety reasons |
| BPC-157, CJC-1295, GHK-Cu and similar | No | Limited human safety data per FDA | Listed on FDA's safety-risk page |
| Menopause hormone therapy | Yes, for symptoms | FDA says it can help hot flashes and night sweats | Clot, stroke and breast cancer risks for some |
| Testosterone | Yes, for hypogonadism from a medical cause | TRAVERSE cardiovascular safety trial | Not established for aging alone; Schedule III |
Sources: FDA: Compounded drugs · FDA: Peptide safety list · FDA: Glutathione injection alert · FDA: Testosterone label changes · FDA: Menopause hormone therapy · Gindri et al., Am J Physiol Endocrinol Metab (2024): NAD systematic review
Are anti-aging injections FDA-approved?
NAD+, glutathione and peptide injections sold by telehealth clinics are compounded, and FDA says compounded drugs are not FDA-approved. FDA-approved hormone products exist, but they are approved for specific conditions such as menopause symptoms or hypogonadism, not for slowing aging.
Sources: FDA: Compounded drugs · FDA: Testosterone label changes · FDA: Menopause hormone therapy
Are NAD+ injections better than NMN or NR supplements?
There is no head-to-head evidence in the reviews we read. A 2024 systematic review found only oral studies, and a 2025 meta-analysis found NMN and NR did not preserve muscle mass or function in older adults.
Sources: Gindri et al., Am J Physiol Endocrinol Metab (2024): NAD systematic review · Prokopidis et al., J Cachexia Sarcopenia Muscle (2025): NMN and NR meta-analysis
Can I get testosterone online for aging?
Testosterone is approved for men with low testosterone tied to a medical condition, and its label says safety and efficacy have not been established for age-related low testosterone. It is a Schedule III controlled substance, so prescribing follows federal and state rules. A clinician decides whether you qualify.
Sources: FDA: Testosterone label changes · DailyMed (NLM): Testosterone cypionate label
Is BPC-157 available from telehealth clinics?
As of FDA's page dated April 22, 2026, BPC-157 is listed as nominated but withdrawn among bulk substances that may present significant safety risks, with FDA noting it has no, or only limited, safety information for the proposed routes. Check FDA's page for the current status before relying on any clinic's claims.
Sources: FDA: Peptide safety list
Sources and editorial notes
Regulatory status and safety notices were checked on FDA pages, the Federal Register and the DailyMed testosterone cypionate label on October 26, 2026. NAD+ evidence comes from two published systematic reviews read via Europe PMC. Provider prices are not quoted here because they change and vary by plan. No clinician review is claimed.
Content updated . Source checking is editorial work; it is not a clinical review.
- FDA: Compounding and the FDA: Questions and AnswersMedical or regulatory reference · Accessed 2026-10-26
- FDA: Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety RisksMedical or regulatory reference · Accessed 2026-10-26
- FDA: FDA reminds compounders not to use dietary supplement grade glutathione in injectablesMedical or regulatory reference · Accessed 2026-10-26
- Federal Register (FDA): Determination That GEREF (Sermorelin Acetate) Injection Was Not Withdrawn From Sale for Reasons of Safety or EffectivenessMedical or regulatory reference · Accessed 2026-10-26
- FDA: FDA Issues Class-Wide Labeling Changes for Testosterone ProductsMedical or regulatory reference · Accessed 2026-10-26
- DailyMed (NLM): DEPO-TESTOSTERONE (testosterone cypionate) injection prescribing informationMedical or regulatory reference · Accessed 2026-10-26
- FDA: MenopauseMedical or regulatory reference · Accessed 2026-10-26
- Gindri et al., Am J Physiol Endocrinol Metab (2024): Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic reviewMedical or regulatory reference · Accessed 2026-10-26
- Prokopidis et al., J Cachexia Sarcopenia Muscle (2025): The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-AnalysisMedical or regulatory reference · Accessed 2026-10-26
Anti-Aging Provider Overview
| Provider | Provider focus | Learn More |
|---|---|---|
| Adults interested in a longevity-focused telehealth platform... | Visit AgelessRx→ Leaving treatment-comparison.com | |
| Adults who want a medically comprehensive anti-aging program... | Visit Defy Medical→ Leaving treatment-comparison.com | |
| Adults who want an affordable, flexible telehealth consultat... | Visit Push Health→ Leaving treatment-comparison.com |
If you are researching anti-aging treatments, treatment-comparison.com provides resources to explore and compare providers, medications, and pricing.
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