Agency is a legitimate prescription skincare service run by Curology, Inc. that focuses on aging skin: a provider licensed in your state reviews your goals, history and photos, then prescribes custom formulas that cost $110 to $130 per 60-day refill (about $55 to $65 a month each). Since its relaunch at agencyskin.com it sells five Rx formulas, for nighttime renewal, daytime antioxidant care, cell repair, dark spots and the eye area, which may include tretinoin, hydroquinone, azelaic acid, tranexamic acid or rapamycin depending on what the provider prescribes. The tradeoffs: ingredient strengths are not published, two or three products add up quickly, the formulas are custom-mixed rather than FDA-approved, and the subscription refills automatically until you cancel.
What We Like
- ✓Built around aging concerns (fine lines, firmness, tone, dark spots) rather than acne
- ✓Published list prices: $130 or $110 per 60-day prescription refill
- ✓Formulas may include established ingredients such as tretinoin, hydroquinone and azelaic acid, which the AAD lists among melasma treatments
- ✓Names its chief dermatologist (Dr. Whitney Tolpinrud, MD, FAAD) and its physician assistant and nurse practitioner providers
- ✓Satisfaction guarantee for first-time subscribers who follow the plan and complete 2 provider check-ins, requested within 120 days
- ✓Cancellation is self-serve in the account's payment section or by email, per the terms
Points to Consider
- ✗Product pages list ingredients a formula "may include" but no strengths, so you only learn your exact formula after the consultation
- ✗Costs stack: a night plus a day formula is $260 per 60 days at list price after the first box
- ✗Custom-mixed formulas are compounded products, and the FDA states compounded drugs are not FDA-approved
- ✗The 50% intro discount applies to the first box only; refills bill automatically a few days before each shipment
- ✗Shipping costs are not shown on the product pages
- ✗Prescription items are not refundable, and the guarantee excludes consultation and shipping fees and is one refund per customer
Key Highlights
- Agency relaunched at agencyskin.com; the old withagency.com address now redirects there
- Five Rx products: Night Renew, Day Defender and Cell Repair at $130, Dark Spot and Eye Revive at $110, each a 60-day supply
- Non-prescription add-ons: Cleansing Balm $40, Whipped Moisturizer $65, Silkscreen SPF 50 $65 and Skin Smoothing Booster $165
- Agency's terms say you must cancel at least 2 business days before your next shipment
Pricing Overview
Night Renew Rx, Day Defender Rx or Cell Repair Rx
Prescription formulas for evening renewal, morning antioxidant care or cell repair. New subscribers get 50% off the first box; refills are charged at the listed price.
$130 per 60-day supply (about $65/mo)
Dark Spot Rx or Eye Revive Rx
Dark Spot targets dark spots and melasma and may include hydroquinone. Eye Revive uses gentler tretinoin levels for the eye area, per Agency.
$110 per 60-day supply (about $55/mo)
Non-prescription essentials
Cleansing Balm $40 (80 mL), Whipped Moisturizer $65 (50 g), Silkscreen SPF 50 mineral sunscreen $65 (40 mL), Skin Smoothing Booster peptide serum $165 (30 mL).
$40 to $165 per item
Shipping and consultation
The product pages do not list shipping or a consultation fee for skin care. The terms exclude consultation and shipping fees from guarantee refunds, so check the full total before you pay.
Confirm at checkout
How It Works
Take the skin quiz
Share your skin goals, medical history and photos through Agency's online sign-up quiz.
A licensed provider prescribes your formulas
Agency says a medical provider licensed in your state tailors the prescription to your concerns, history and photos. Ingredients and strengths are decided in this step.
Formulas ship from a contracted pharmacy
Agency's terms say dermatology products are dispensed by contracted pharmacies. Each prescription product is a 60-day supply.
Check in, adjust or cancel
Providers adjust the regimen over time. Refills ship automatically and are charged a few days before each shipment; cancel at least 2 business days ahead to stop the next one.
The Bottom Line
Agency suits adults whose main goal is aging skin or dark spots and who want a provider to choose prescription ingredients such as tretinoin or hydroquinone for them. At $110 to $130 per 60-day refill per product it is not a budget option, and you will not see your exact strengths until after the consultation. Ask the provider which ingredients are in your formula, note the date of your next refill, and if acne is your main concern, compare Curology, which is run by the same company and lists acne, rosacea and dark spots as its focus.
Frequently Asked Questions
Agency prescription formulas and published prices
Prices are the list prices shown on agencyskin.com on October 25, 2026. Each prescription product is a 60-day supply, so $130 works out to about $65 a month and $110 to about $55 a month. New subscribers get 50% off the first box; later refills are charged at the listed price a few days before each shipment, per Agency's terms. The pages do not list shipping costs or ingredient strengths.
| Product | Aimed at | Ingredients the formula may include | Price per 60 days |
|---|---|---|---|
| Night Renew Rx (24 g) | Fine lines, firmness, uneven tone, redness | Tretinoin, tranexamic acid, azelaic acid, niacinamide, estriol, dexpanthenol | $130 |
| Day Defender Rx (24 g) | Morning antioxidant care, brightness | Vitamin C at a customizable strength plus antioxidants | $130 |
| Cell Repair Rx (24 g) | Firmness, tone, barrier | Rapamycin, resveratrol | $130 |
| Dark Spot Rx (18 g) | Dark spots, melasma, uneven tone | Hydroquinone, azelaic acid, kojic acid, hydrocortisone, resveratrol, green tea extract | $110 |
| Eye Revive Rx (12 g) | Fine lines and crow's feet around the eyes | Tretinoin, caffeine, dexpanthenol, green tea extract | $110 |
Sources: Agency: Agency product list · Agency: Night Renew page · Agency: Day Defender page · Agency: Cell Repair page · Agency: Dark Spot page · Agency: Eye Revive page · Agency: Agency terms
Questions to ask the Agency provider
- Which ingredients and what strengths are in my formula? The product pages say ingredients are subject to consultation and list no percentages.
- Am I pregnant, planning a pregnancy or breastfeeding? MedlinePlus says to tell your doctor before using tretinoin, and Agency's Eye Revive page says the same.
- Does my formula contain estriol, hydroquinone or rapamycin, and is each one right for my health history?
- Is my discoloration melasma or sun damage? The AAD says melasma results usually take 3 to 12 months and that daily broad-spectrum sunscreen matters.
- How do I stop before the next refill? Agency's terms require canceling at least 2 business days before the next shipment.
Sources: Agency: Eye Revive page · Agency: Agency terms · American Academy of Dermatology: AAD melasma treatment · MedlinePlus (NIH): MedlinePlus tretinoin
Sources and editorial notes
Products, prices, ingredients, provider details and subscription terms come from Agency's own product pages, provider page and Terms of Service (last updated October 22, 2026), opened on October 25, 2026. Medical context comes from the FDA's compounding page, the American Academy of Dermatology and MedlinePlus. We did not order, consult or verify a personalized price, and no clinician review is claimed.
Content updated . Source checking is editorial work; it is not a clinical review.
- Agency: Agency skin longevity home pageProvider-reported product information · Accessed 2026-10-25
- Agency: Agency products and pricesProvider-reported product information · Accessed 2026-10-25
- Agency: Night Renew RxProvider-reported product information · Accessed 2026-10-25
- Agency: Day Defender RxProvider-reported product information · Accessed 2026-10-25
- Agency: Cell Repair RxProvider-reported product information · Accessed 2026-10-25
- Agency: Dark Spot RxProvider-reported product information · Accessed 2026-10-25
- Agency: Eye Revive RxProvider-reported product information · Accessed 2026-10-25
- Agency: Agency medical providersProvider-reported product information · Accessed 2026-10-25
- Agency: Agency Terms of Service (last updated October 22, 2026)Provider-reported product information · Accessed 2026-10-25
- Curology: Curology home pageProvider-reported product information · Accessed 2026-10-25
- FDA: Human Drug Compounding LawsMedical or regulatory reference · Accessed 2026-10-25
- American Academy of Dermatology: Melasma: Diagnosis and treatmentMedical or regulatory reference · Accessed 2026-10-25
- MedlinePlus (NIH): Tretinoin TopicalMedical or regulatory reference · Accessed 2026-10-25