Erectile Dysfunction Medications Guide

Sildenafil citrate — 25mg, 50mg, or 100mg taken as needed, roughly 30-60 minutes before sexual activity. Most providers suggest not exceeding one dose per day.

Men who want an affordable, well-studied, as-needed option for erectile dysfunction

Tadalafil — 2.5mg or 5mg daily, or 10mg-20mg as needed roughly 30 minutes before sexual activity. Should not exceed one dose per day.

Men who prefer a daily option or want a longer-lasting medication that may allow for more spontaneity

Vardenafil hydrochloride — 5mg, 10mg, or 20mg taken as needed, approximately 60 minutes before sexual activity. Should not exceed one dose per day.

Men who may not have responded well to sildenafil or who prefer a slightly different side-effect profile

Compounded sildenafil, tadalafil, or combination formulations — Varies widely by product. Chewables and sublingual troches are typically taken 15-30 minutes before sexual activity. Dosage depends on the active ingredients and combination used.

Men who have difficulty swallowing pills, want faster onset through sublingual absorption, or prefer combination formulations

Avanafil — 50mg, 100mg, or 200mg taken as needed, approximately 15-30 minutes before sexual activity. Should not exceed one dose per day.

Men who want the fastest possible onset of action and are willing to pay a premium