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Tadalafil (Generic Cialis)
genericFDA-approved generic since 2018
Est. Cost
$1.80-$10/pill
/month
Tadalafil is the generic version of Cialis and is widely recognized for its extended duration of action. Unlike sildenafil, tadalafil can be taken daily at a low dose or as needed at a higher dose, offering flexibility depending on individual preference. Its long-lasting effects have made it a popular choice for men who want to avoid timing a pill around sexual activity.
Dosage Format
2.5mg or 5mg daily, or 10mg-20mg as needed roughly 30 minutes before sexual activity. Should not exceed one dose per day.
Type
Generic
Best For
Men who prefer a daily option or want a longer-lasting medication that may allow for more spontaneity
Key Benefit
Often called the 'weekend pill' because its effects may last up to 36 hours — significantly longer than other PDE5 inhibitors.
Where to Get Tadalafil (Generic Cialis)
Compare providers offering tadalafil (generic cialis) — ranked by our editorial team
Hims
Available as daily or as-needed prescriptions; includes online consultation and ongoing provider access.
$2-$6/dose
/month
Ro
Online provider visit included; can be prescribed as daily or as-needed with home delivery.
$3-$8/dose
/month
BlueChew
Offered in chewable tablet form; subscription model with multiple plan tiers available.
$3/dose
/month
Rex MD
One of the more affordable daily tadalafil options; includes online evaluation and discreet shipping.
$1.80/dose (daily)
/month
How Tadalafil (Generic Cialis) Works
Like sildenafil, tadalafil is a PDE5 inhibitor that may help increase blood flow to the penis by blocking the enzyme that breaks down cGMP. What sets tadalafil apart is its longer half-life — roughly 17.5 hours — which means its effects can potentially last up to 36 hours. At a daily dose of 2.5mg or 5mg, tadalafil may maintain a steady level in the body, potentially allowing for erections whenever sexually aroused without needing to plan around a pill. Sexual stimulation is still required.
Side Effects
Common
- • Headache
- • Indigestion or acid reflux
- • Back pain
- • Muscle aches
- • Nasal congestion
- • Facial flushing
Serious (Rare)
- • Priapism (an erection lasting more than 4 hours) — seek emergency medical attention
- • Sudden vision loss or changes
- • Sudden hearing decrease or loss
- • Chest pain, especially during or after sexual activity
- • Severe dizziness or fainting
Who Is Eligible
Tadalafil is typically prescribed to adult men diagnosed with erectile dysfunction. It should not be taken alongside nitrate medications or certain alpha-blockers without medical guidance. Men with liver or kidney concerns, heart conditions, or a history of stroke should discuss risks carefully with a provider before starting tadalafil.